MCQs for CSIR NET & GATE
Bioinorganic Chemistry
Topicwise Assignment-1
Q1. Storage of Iron in human body is carried out by
(a) Myoglobin
(b) Ferritin
(c) Hemoglobin
(d) Cytochrome P50
Q2. Myoglobin is
(a) catalyst for epoxidation reaction
(b) component in photosynthetic system
(c) nitrogen fixation enzyme
(d) di-oxygen binding metalloprotein
Q3. Which of the following statement for hemoglobin is incorrect?
(a) the binding with O2 is weaker in comparison with myoglobin.
(b) iron is 5-coordinated.
(c) iron is co-planer with the porphyrin ring in the absence of oxygen.
(d) oxidation state of iron is +2.
Q4. In the transformation of oxy-hemoglobin to deoxy-hemoglobin
(a) Fe2+ in the low spin state changes to Fe2+ in the high oxidation state
(b) Fe2+ in the low spin state changes to Fe3+ in the low oxidation state
(c) Fe2+ in the high spin state changes to Fe2+ in the low oxidation state
(d) Fe2+ in the high spin state changes to Fe3+ in the high oxidation state
Q5. In oxy-hemoglobin, the iron centre is best described by which of the following?
(a) high spin Fe(III)
(b) high spin Fe(II)
(c) low spin Fe(III)
(d) low spin Fe(II)
Q6. Hemoglobin is an oxygen carrying protein. The correct statement about oxy-hemoglobin is that
(a) the metal is low spin in +3 oxidation state while dioxygen is in O2‑ form
(b) the metal is high spin in +3 oxidation state while dioxygen is in O2+ form
(c) the metal is low spin in +3 oxidation state while dioxygen is in neutral form
(d) the metal is high spin in +3 oxidation state while dioxygen is in neutral form
Q7. The oxidation state of iron in met-hemoglobin is
(a) 3
(b) 2
(c) 4
(d) 0
Q8. The cooperative binding of O2 in hemoglobin is due to
(a) a decrease in the size of iron followed by changes in the protein conformation.
(b) a increase in the size of iron followed by changes in the protein conformation.
(c) a decrease in the size of iron NOT followed by changes in the protein conformation.
(d) a increase in the size of iron NOT followed by changes in the protein conformation.
Q9. Under physiological condition, oxygen is binding to deoxy-hemoglobin and deoxy-myoglobin, the binding curve and it’s pH dependence respectively are
(a) sigmoidal & pH dependent; hyperbolic and pH independent.
(b) hyperbolic and pH independent; sigmoidal & pH dependent.
(c) sigmoidal & pH independent; hyperbolic and pH dependent.
(d) hyperbolic and pH independent; sigmoidal & pH dependent.
Q10. Among the given pH values, the O2 binding efficiency of hemoglobin is maximum at
(a) 6.8
(b) 7.0
(c) 7.2
(d) 7.4
Ans Key
Q1.b Q2.d Q3.c Q4.a Q5.d Q6.a Q7.c Q8.a Q9.a Q10.d